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AI Ascent 2025

Sequoia convened builders and researchers in AI for another packed day of conversations, talks and demos.

On May 2, we hosted our third AI Ascent event in San Francisco, bringing together more than 100 leading founders and researchers in AI to engage with what partner Pat Grady calls, the “tremendous sucking sound in the market” for AI, and his advice to “go at maximum velocity, all of the time.” Partner Sonya Huang talked about the improved retention rate of generative AI applications and pronounced that coding had reached “screaming product-market fit.” And partner Konstantine Buhler looked ahead to how the agent economy will transform how we work, and laid out the technologies we need to get there.

Over the course of the day we talked with AI leaders including Sam Altman of OpenAI, Jensen Huang and Jim Fan of Nvidia, Jeff Dean of Google, Mike Krieger of Anthropic, Bret Taylor of Sierra and many more. The talks ranged from new business models for AI agents, the race to build data centers, the power of vertical applications and the importance of open source.

Below is a selection of videos from the event (some sessions were off the record).

Videos from AI Ascent 2025

You can also watch the videos on the AI Ascent 2025 YouTube playlist.

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